I found out that one of the recent updates to Chrome included the ability to lock the mouse cursor. So I rolled out an update for Chromemote (beta ver 0.1211.5) over the weekend that now includes the ability to lock your cursor to the Google TV. Unfortunately the features is not supported within the Chromemote popup window, but if you go to the pinned/tabbed mode of Chromemote, you can click the cursor button to lock your mouse to the screen. Simple press ESC to return control. I also corrected an issue with the direction pad which caused Chromemote to send multiple commands for a single press.